何振艳 研究组
何振艳，女，博士，研究员，博士生导师
办公室：牡丹楼 E127
电话：010-62836690
个人简介:
1998年和2001年在山西农业大学获学士和硕士学位，2004年在中科院植物所获博士学位。现任中科院植物所副研究员，中国植物生理学会修复生物学专业委员会委员，中国花卉协会蕨类植物分会理事，北京植物学会理事。迄今承担国家自然科学基金项目、国家重点研发计划、国家高技术研究发展计划、科技基础性工作重大专项、中科院先导专项等多个项目；获得国家授权专利10余项；在Nature Communications、Journal of Hazardous Materials、New Phytologist等刊物上发表论文30余篇。
主要研究内容:
利用分子生物学技术，结合遗传学、细胞生物学和蛋白质组学等方法研究植物对重金属的分子响应机制，着重两方面的应用开发：一是基于超富集植物分子基础的重金属污染修复技术研发；二是基于稳定分子标记技术的低积累重金属安全作物新品种的培育。
科研项目:
• 国家自然科学基金面上项目，蜈蚣草PvABCT1相互作用蛋白的分离与功能研究
• 国家自然科学基金面上项目，蜈蚣草羽叶砷响应的差异蛋白质组学（DIGE）研究
• 国家自然科学基金面上项目，蜈蚣草砷液泡区隔化基因的挖掘和功能分析及其应用研究
• 国家自然科学基金面上项目，基于全长转录组的蜈蚣草砷转运水通道蛋白的挖掘和深入解析
• 国家自然科学基金面上项目，蜈蚣草砷转运PvABCs蛋白的功能解析及应用探究
• 国家高技术研究发展计划，特殊生境植物资源的开发利用技术
• 科技基础性工作重大专项子课题，我国大豆重金属污染调查
• 国家重点研发计划子课题，重金属低积累玉米品种筛选及评比技术研究
• 中科院先导专项子任务，北方稻区水稻镉污染现状及分子模块解析
• 中科院先导专项任务，水稻籽粒重金属低积累的分子网络
• 中科院先导专项任务，甜高粱品质安全性状解析与新品种定向分子选育
• 横向项目，植物修复重金属污染土壤的评价
发表论文:
• Feng L, Yan HL, Dai CH, Xu WX, Gu FY, Zhang F, Li T, Xian JY, He XQ, Yu YJ, Ma M, Wang F* & He ZY*. 2020. The systematic exploration of cadmium-accumulation characteristics of maize kernel in acidic soil with different pollution levels in China. Science of the Total Environment, 729: 138972.
• Liu ZQ, Li HL, Zeng XJ, Lu C, Fu JY, Guo LJ, Kimani WM, Yan HL, He ZY, Hao HQ*. Jing HC. 2020. Coupling phytoremediation of cadmium-contaminated soil with safe crop production based on a sorghum farming system. Journal of Cleaner Production, 275: 123002.
• Zhang F, Gu FY, Yan HL, He ZY, Wang BL, Liu H, Yang TT, Wang F*. 2020. Effects of soaking process on arsenic and other mineral elements in brown rice. Food Science and Human Wellness, 9(2): 168-175
• Yan HL, Xu WX, Xie JY, Gao YW, Wu LL, Sun L, Feng L, Chen X, Zhang T, Dai CH, Li T, Lin XN, Zhang ZY, Wang XQ, Li FM, Zhu XY, Li JJ, Li ZC, Chen CY, Ma, M, Zhang HL* & He ZY*. 2019. Variation of a major facilitator superfamily gene contributes to differential cadmium accumulation between rice subspecies. Nature Communications, 10: 2562.
• Yan HL, Gao YW, Wu LL, Wang LY, Zhang T, Dai CH, Xu WX, Feng L, Ma M, Zhu YG*, He ZY*. 2019. Potential use of the Pteris vittata arsenic hyperaccumulation-regulation network for phytoremediation. Journal of Hazardous Materials, 368: 386-396.
• Zhang T, Xu WX, Lin XN, Yan HL, Ma M, He ZY*. 2019. Assessment of heavy metals pollution of soybean grains in North Anhui of China. Science of The Total Environment, 646: 914-922.
• 张田，闫慧莉，何振艳*．2019.蜈蚣草中砷超富集的分子机制研究进展[J/OL]．生物工程学报. https://doi.org/10.13345/j.cjb.190374.
• He ZY, Yan HL, Chen YS, Shen HL, Xu WX, Zhang HY, Shi L, Zhu YG, Ma M. 2016. An aquaporin PvTIP4;1 from Pteris vittata may mediate arsenite uptake. New Phytologist, 209: 746-761.
• Sun YY, Xu WZ, Wu L, Wang RZ, He ZY, Ma M. 2016. An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance. Plant, Cell & Environment, 39：416-426.
• Xu WZ, Dai WT, Yan HL, Li S, Shen HL, Chen YS, Xu H, Sun YY, He ZY, Ma M. 2015. Arabidopsis NIP3;1 plays an important role in arsenic uptake and root-to-shoot translocation under arsenite stress conditions. Molecular Plant, 8: 722-733.
• Shen HL, He ZY*, Yan HL, Xing ZN, Chen YS, Xu WX, Xu WZ, Ma M. 2014. The fronds tonoplast quantitative proteomic analysis in arsenic hyperaccumulator Pteris vittata L. Journal of Proteomics, 105: 46-57.
• Dai WT, Yang XX, Chen H, Xu WZ, He ZY, Ma M. 2013. Phytotoxicities of inorganic arsenic and dimethylarsinic acid to Arabidopsis thaliana and Pteris vittata. Bulletin of Environmental Contamination and Toxicology, 91(6): 652-655.
• Chen YS, Xu WZ, Shen HL, Yan HL, Xu WX, He ZY, Ma M. 2013. Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation by a PvACR3 transgenic approach. Environmental Science &Technology, 47: 9355-9362.
• Xu H, Xu WZ, Xi HM, Ma WW, He ZY, Ma M. 2013. The ER luminal binding protein (BiP) alleviates Cd2%2b-induced programmed cell death through endoplasmic reticulum stress–cell death signaling pathway in tobacco cells. Journal of Plant Physiology, 170: 1434-1441.
• Ma WW, Xu WZ, Xu H, Chen YS, He ZY, Ma M. 2010. Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 suspension cultures. Planta, 232: 325-335.
• Yang XX, Chen H, Dai XJ, Xu WZ, He ZY, Ma M. 2009. Evidence of vacuolar compartmentalization of arsenic in the hyperaccumulator Pteris vittata. Chinese Science Bulletin, 54: 4229-4233.
• Zheng YQ, Dai XJ, Wang L, Xu WZ, He ZY, Ma M. 2008. Arsenate reduces copper phytotoxicity in gametophytes of Pteris vittata. Journal of Plant Physiology, 165: 1906-1916.
• Zheng YQ, Xu WZ, He ZY, Ma M. 2008. Plant regeneration of the arsenic hyperaccumulator Pteris vittata L. from spores and identification of its tolerance and accumulation of arsenic and copper. Acta Physiologiae Plantarum, 30: 249-255.
• Yang XX, Chen H, Xu WZ, He ZY, Ma M. 2007. Hyperaccumulation of arsenic by callus, sporophytes and gametophytes of Pteris vittata cultured in vitro. Plant Cell Reports, 26: 1889-1897.
• Zhang HY, Xu WZ, Dai WT, He ZY, Ma M. 2006. Functional characterization of cadmium-responsive garlic gene AsMT2b: A new member of metallothionein family. Chinese Science Bulletin, 51: 409-416.
• He ZY, Li JC, Zhang HY, Ma M. 2005. Different effects of calcium and lanthanum on the expression of phytochelatin synthase gene and cadmium absorption in Lactuca sativa. Plant Science, 168: 309-318.
• Zhang HY, Jiang YN, He ZY, Ma M. 2005. Cadmium tolerance and antioxidative responses of the garlic plant. Journal of Plant Physiology, 162: 977-984.
• Zhang HY, Xu WZ, Guo JB, He ZY, Ma M. 2005. Coordinated responses of phytochelatins and metallothioneins to heavy metals in garlic seedlings. Plant Science, 169: 1059-1065
• 何振艳，徐文忠，杨学习，麻密. 2005. 蜈蚣草高质量总RNA提取的一种有效方法. 植物学通报, 22(2): 198-202.
国家发明专利
• 培育低镉积累水稻的方法及其相关材料的用途，专利号：ZL 201711001191.3
• 水稻籽粒镉含量相关基因LCd-41的SNP分子标记的应用，专利号：ZL 201610121407.9
• 水稻籽粒镉含量相关基因LCd-22的SNP分子标记的应用，专利号：ZL 201610113156.X
• 水稻籽粒镉含量相关基因LCd-38的SNP分子标记的应用，专利号：ZL 201610108474.7
• 水稻籽粒镉含量相关基因LCd-31的SNP分子标记的应用，专利号：ZL 201610172662.6
• 水稻籽粒镉含量相关基因LCd-11的SNP分子标记的应用，专利号：ZL 201610104530.X
• 一种植物砷抗性相关的蛋白及编码基因及其应用，专利号：ZL 201010116 397.2
• 一种蛋白及其编码基因与应用，专利号：ZL 201010528752.7
• 一种蜈蚣草ABC转运蛋白及其编码基因与应用，专利号：ZL 200410080857.5
• 一种降低镉在植物中积累的方法及其应用，专利号：ZL 03157195.6
• 一种检测植物中目标蛋白的方法及其专用SPR生物传感器，专利号：ZL 201110081230.1
• 一种培育低重金属积累植物的方法，专利号：ZL 200410096858.9
• 一种蜈蚣草经绿色球状体再生植株的方法及其专用培养基, 专利号：ZL 200810239942.X
• 一种与砷响应相关的调控片段及其应用，专利号：ZL 2010 0128600.8